Outside of kidney function, several other factors can temporarily raise creatinine levels above normal. These include dehydration and consuming large amounts of protein — either through food sources or nutritional supplements. High intensity exercise can also increase certain blood biomarkers, including creatinine.
Creatinine levels can also rise temporarily from strenuous exercise or using certain medications like sulfamethoxazole, trimethoprim, or chemotherapy drugs . Furthermore, becoming pregnant or eating a diet high in red meat may contribute. Your body needs to clean your blood to function optimally.
Cimetidine (Tagamet) and ranitidine (Zantac) are acid blockers, or H2-blockers, used for acid reflux and heartburn symptoms, and they are a common cause of a falsely elevated creatinine test, according to a 2012 review of related researc
Flucytosine is the only agent known to cause a false elevated creatinine result when this method is used . 6 This artificial result is attributed to the 4-amino group of flucytosine, which is converted to free ammonia by creatine iminohydrolase.
High serum creatinine levels in the blood indicate that the kidneys aren't functioning properly. Your serum creatinine levels may be slightly elevated or higher than normal due to: a blocked urinary tract . a high-protein diet.
Several drugs, such as cimetidine, trimethoprim, corticosteroids, pyrimethamine, phenacemide, salicylates and active vitamin D metabolites , have been reported to increase plasma creatinine without influencing its glomerular filtration.
They generally do not correlate with the level of creatinine in the blood. Some people may have an incidental finding of severe kidney disease and elevated creatinine on routine blood work without having any symptoms .
Outside of kidney function, several other factors can temporarily raise creatinine levels above normal. These include dehydration and consuming large amounts of protein — either through food sources or nutritional supplements. High intensity exercise can also increase certain blood biomarkers, including creatinin
Creatinine levels can change rapidly, even throughout the day , which is why healthcare providers monitor them for an extended period of time. One blood test that returns high creatinine in blood could be a fluke. However, several tests in a row that show elevated levels could indicate chronic kidney diseas
As creatinine levels can fluctuate a fair bit depending on your level of activity, recent fluid intake and of course illnesses , it is important not to worry about small changes in your creatinine level. Longer term trends are far more relevant.